Agentic self-driving microscopy benchmarks support qualification but do not necessarily generalize to unseen tasks

arXiv cs.AIAugust 7, 2026en

arXiv:2608.05266v1 Announce Type: new Abstract: Large language model agents are increasingly being developed to control a wide range of scientific characterization tools including microscopes and synchrotron beamlines. Research into agentic control of physical infrastructure is nascent and there are few well-established paradigms for how to engineer an agentic system. There are many choices to make when designing a microscopy agent, including the choice of LLM, the number of agents to use, agent responsibilities and delegation rules, retrieval-augmented generation parameters, and more. When designing and optimizing an agentic microscope controller, researchers not only want to ensure that th

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