Asclepius: An Adaptive Harness for Long-Horizon Clinical Agents

arXiv cs.AISeptember 15, 2026en

arXiv:2609.13543v1 Announce Type: new Abstract: LLM agents are predominantly benchmarked on short, single-task trajectories, yet real deployments run for hours under contention, surfacing a different class of failures. We use the Clinical Environment Simulator (CES), in which an agent manages an entire emergency-department shift under continuous time and resource pressure, as a testbed: long-horizon execution failures manifest measurably in a single rollout under structured, multi-dimensional grading. On CES, current agents reach the correct diagnosis in most cases yet fail to deliver complete and timely critical actions, revealing an execution gap. We attribute this gap to three long-horizo

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