Do AI-for-Science Agents Preserve Model Safety?

arXiv cs.AIOctober 26, 2026en

arXiv cs.AI

AI Global Wire

arXiv:2610.32045v1 Announce Type: new Abstract: AI-for-Science agents are increasingly being used for formulating scientific hypotheses, running autonomous experiments, and interpreting evidence. These agents are constructed by integrating a large language model (LLM) into a domain-specific agent harness, which in turn can improve the LLM's scientific capability and enable the model to orchestrate scientific tools. In this work, we ask whether model safety is preserved when an LLM is integrated in an AI-for-Science agent harness. We evaluate five agent harnesses on 50 harmful chemistry requests. Specifically, we study how the safety behavior changes under direct prompting, two simple adversa

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