Large Language Models in Mental Health: A Systematic Review of Applications, Innovations, and Ethical Challenges

arXiv cs.AIAugust 20, 2026en

arXiv:2608.18080v1 Announce Type: new Abstract: We present a review on the applications of large language models (LLMs) in health, e.g., social media analysis, clinical conversational agents, therapy support tools, prompt engineering, multimodal learning, and ethical considerations. We integrate findings from interdisciplinary studies utilizing diverse data sources such as social media posts, electronic medical records, and multimodal inputs to enable early detection of depression, suicide risk assessment, personalized therapy support, and psychoeducational content generation. Our review highlights advancements in LLM models and annotation strategies that enhance interpretability and clinica

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