CRISS: A Retrieval-Augmented AI Chatbot for Assisting Cancer Registrars

arXiv cs.AISeptember 25, 2026en

arXiv:2609.29075v1 Announce Type: new Abstract: Cancer registrars, including Oncology Data Specialists (ODSs), must interpret complex and frequently updated coding and staging standards. We developed CRISS (Cancer Registry Intelligent Support System), a retrieval-augmented generation (RAG) conversational assistant that provides rapid, citation-supported access to registry guidance. This study evaluated whether CRISS could (1) support accurate and citation-supported responses, (2) improve access to and interpretation of relevant guidance, and (3) support training/helpdesk use while preserving human oversight of final abstraction decisions. We built a domain-specific knowledge base from nation

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